Extracellular Matrix (ECM) Patches
Biological augmentation with ECM patches has emerged as a valuable adjunct for complex rotator cuff repairs. These patches provide both mechanical reinforcement and biological enhancement of the healing environment, serving as scaffolds for tissue regeneration while reducing the mechanical stress on the repair site.
Human Dermal Matrix
Provides excellent integration with host tissue with low inflammatory reaction. This is the most commonly used patch in our practice. Best suited for large tears at risk and revision situations.
Animal (porcine/bovine) Dermal Matrix
Cross-linked collagen matrix used over the top of a repair. Can have an inflammatory response in some patient. Clinical studies show 78% intact repairs at 2-year follow-up with improved functional outcomes compared to repair alone.
Synthetic Patches
PEEK and polyester patches provide durable mechanical support. Consider when maximum mechanical support is needed.
Autologous biceps Tendon Patches
Created from the patient's own biceps tendon, which is compressed in a mold to create a postage-stamp sized patch to lay over the rotator cuff repair. These patched have shown substantial numbers active tenocytes that may help with rotator cuff repair healing.
Level I Evidence
A randomized controlled trial of 165 patients showed that ECM augmentation in large to massive tears (>3cm) resulted in significantly lower re-tear rates at 24 months (17% vs 35%, p<0.001). The Number Needed to Treat was 5.6 patients to prevent one re-tear.
Indications for Patch Augmentation
• Large to massive tears (≥3 cm) with poor tissue quality
• Revision rotator cuff repairs
• Tears with fatty atrophy
• Tears with significant retraction and/or poor tendon stump
• High demand patients with heavy work duties
• Consider cost-effectiveness in appropriate candidates
Picking a repair construct must take into account many factors, which will depend on the tear configuration and size, tissue quality, bone quality, and amount of tension on the repair. With modern rotator cuff repair, there are a plethora of implant options to help us cater to each specific circumstance. We aim to maximize both the biological environment and mechanical strength of the repair.
Double-Row and Suture Bridge Techniques
Advanced repair constructs have revolutionized rotator cuff surgery by improving footprint restoration and load distribution. These techniques create more anatomic repairs with superior biomechanical properties compared to traditional single-row repairs.
Suture Bridge Configuration
Creates optimal pressure distribution across the footprint. Biomechanical studies show 35% greater contact area and 50% higher pressure compared to initial double-row repairs. Clinical healing rates approach 90% in appropriate tears.
Transosseous-Equivalent Repair
Mimics gold standard transosseous repair using modern anchors. Provides 40% greater ultimate load to failure. Meta-analysis shows superior structural integrity at 2 years (82% vs 68%).
Knotless Speed Bridge
Eliminates knot-related complications while maintaining consistent tension. Reduces operative time by 15-20 minutes. Clinical studies demonstrate equivalent healing with improved patient satisfaction scores.
Load-Sharing Repair
Novel technique distributing forces across multiple anchor points. Early studies show promise in massive tears with reduced gap formation and improved early healing response.
Biomechanical Evidence
Systematic review of 28 biomechanical studies confirms double-row constructs demonstrate mean 71% greater ultimate load to failure (289N vs 169N, p<0.001) and 84% greater stiffness compared to single-row repairs. Gap formation reduced by 60% under cyclic loading.
Technical Considerations
• Proper tensioning crucial - aim for 30-40N tension per suture
• Lateral row placement 5-8mm lateral to greater tuberosity
• Avoid over-compression leading to strangulation
• Consider tissue quality when selecting construct complexity
Long Head Biceps Tendon (LHBT) as Biological Augmentation
The long head biceps tendon offers excellent biological augmentation potential for complex rotator cuff repairs. This autologous tissue provides both structural support and biological enhancement without the costs and potential complications of allograft materials. The biceps can be used instead of a traditional patch augmentation as listed above.
Biceps Augmentation Technique
LHBT augments primary repair in high-risk tears. Clinical series demonstrate 92% healing rates in tears >4cm. Provides biological enhancement without compromising biceps function when properly tensioned.
Biceps Rerouting
Rerouting LHBT for superior capsular reconstruction. Early studies show promise in increasing healing rates. The biceps tendon is moved from its more anterior position and placed towards the superior aspect of the joint to take load off the rotator cuff repair.
Clinical Outcomes
Multicenter study of 247 patients undergoing biceps augmentation showed mean ASES scores improved from 42 to 89 points at final follow-up. Re-tear rate was 12% compared to historical controls of 35% for massive tears without augmentation.
Patient Selection Criteria
Optimal candidates for biceps augmentation include patients with large/massive tears, good tissue quality of remaining cuff, absence of significant fatty infiltration, and reasonable expectations. Contraindications include active biceps pathology, previous biceps surgery, and significant muscle atrophy.
Surgical Pearls
• Assess biceps quality intraoperatively - reject if degenerative
• Maintain adequate length for tension-free repair
• Consider concurrent biceps tenodesis at completion
• Modified rehabilitation may be necessary to protect augmentation
Nutritional Optimization for Tendon Healing
Emerging evidence demonstrates that nutritional status significantly impacts rotator cuff healing. Targeted nutritional interventions can optimize the biological environment for tissue repair and reduce complications.
Vitamin C
Collagen synthesis cofactor
1000-2000mg daily
Protein
Amino acids for tissue repair
1.2-1.6 g/kg body weight
Magnesium
Helps with Vitamin C and D absorption and helps with tendon healing
up to 300mg daily
Vitamin D
Bone metabolism, muscle function
2000-4000 IU daily
Omega-3 Fatty Acids
Anti-inflammatory effects
2-3g EPA/DHA daily
Zinc
Metalloproteinase function
15-20mg daily
Arginine
Nitric oxide synthesis, wound healing
10-15g daily
Nutritional Impact on Healing
Prospective study of 180 patients showed that preoperative nutritional optimization (protein >1.2g/kg/day, Vitamin C >1000mg/day, Vitamin D >30ng/mL) resulted in 23% faster healing on MRI at 6 months and 15% lower complication rates compared to standard care.
Medical Comorbidity Management
Systematic management of medical comorbidities significantly impacts rotator cuff healing outcomes. Evidence-based optimization protocols should be implemented preoperatively.
Diabetes Management
HbA1c <7% associated with improved healing rates. Consider delaying surgery if HbA1c >8%. Continuous glucose monitoring may benefit perioperative management.
Smoking Cessation
Minimum 4-week cessation recommended. Nicotine replacement therapy acceptable. Studies show 3x higher healing rates with cessation >4 weeks preoperatively.
BMI Optimization
BMI >35 associated with increased complications. Consider structured weight loss programs preoperatively. Even 10% weight loss improves outcomes significantly.
Sleep Apnea Screening
High prevalence in rotator cuff patients. CPAP compliance improves tissue oxygenation and healing. Screen with STOP-BANG questionnaire.
Optimization Timeline
• Begin nutritional supplementation 4-6 weeks preoperatively
• Achieve glycemic control (HbA1c <7%) before surgery
• Smoking cessation minimum 4 weeks prior
• Continue optimization protocols 12 weeks postoperatively
• Consider delayed surgery for suboptimal patients when possible
Inflammation and Pain Management
A balanced approach to inflammation management is crucial for optimal healing. While some inflammatory response is necessary for healing, excessive inflammation can impair tissue repair and lead to poor outcomes.
Anti-inflammatory Strategy
Systematic reviews suggests selective COX-2 inhibitors may be preferable to traditional NSAIDs in the early healing phase (0-6 weeks). Corticosteroid injections should be avoided within 3 months of surgery due to deleterious effects on tendon healing.
Dr. Daniel Elkin is a leading Orthopedic Surgeon performing Rotator Cuff Surgery in the Willamette Valley. He specializes in complex shoulder reconstruction and shoulder arthroscopy and is conveniently located in Salem, Oregon
Copyright © 2025 Dr Daniel Elkin
Orthopedic Surgeon, Sports Medicine, Knee, Shoulder - Salem, or
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